Low - Molecular Weight Heparins and Unfractionated Heparins during Primary Coronary Intervention

Author(s): Chiara Cavallino, Matteo Santagostino, Emanuela Facchini, Virginia Di Ruocco, Andrea Rognoni.

Journal Name:Cardiovascular & Hematological Agents in Medicinal Chemistry

Volume 11 , Issue 2 , 2013

Abstract:

Coronary artery diseases continue to be the most common causes of mortality and morbidity in the industrialized world, especially in the setting of acute myocardial infarction.

Anticoagulation during primary percutaneous coronary intervention (PCI) for ST-elevation myocardial infarction (STEMI) has traditionally been supported by anticoagulant unfractionated heparin (UFH). Recently, alternative anticoagulants such as low molecular weight heparin (LMWH) were included in the management of STEMI.

The aim of the present review is to compare efficacy and safety outcomes among patients receiving low molecular weight heparins (LMWH) or unfractionated heparin (UFH) while undergoing PCI for STEMI.

Keywords: STEMI, PCI, low-molecular weight heparins, unfractionated heparin, acute coronary syndromes, thrombosis, in – stent restenosis, bleeding, coronary intervention, adjuvant therapy.

Rights & PermissionsPrintExport

Article Details

VOLUME: 11
ISSUE: 2
Year: 2013
Page: [96 - 100]
Pages: 5
DOI: 10.2174/1871525711311020004
Price: $58