Malaria is an infectious disease causing almost one million deaths each year. There is an urgent need for
discovery of new antimalarial compounds. Natural products have been the single most productive source of leads for the
development of drugs, because of their great variety of chemical structures. This review covers studies on antimalarial
natural products isolated from plants, published from January 2010 until April 2012. A total of 171 structures comprising
alkaloids, terpenoids, phenolics and other metabolites are listed in this review, including information on their
antiplasmodial and cytotoxic activity.
Keywords: Malaria, antimalarial, Plasmodium, antiplasmodial, natural product.
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