Facile N-Nitrosation of Secondary Amines Using Poly(N,N'-dibromo-Nethylene- benzene-1,3-disulfonamide)and N,N,N',N'-tetrabromobenzene- 1,3-disulfonamide/NaNO2 Under Mild Conditions

Author(s): Ramin Ghorbani-Vaghei, Lotfi Shiri, Arash Ghorbani-Choghamarani.

Journal Name: Letters in Organic Chemistry

Volume 10 , Issue 3 , 2013

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Abstract:

In this research project, a combination of poly(N,N'-dibromo-N-ethylene-benzene-1,3-disulfonamide) [PBBS] and/or(N,N,N',N'-tetrabromobenzene-1,3-disulfonamide) [TBBDA] with sodium nitrite in the presence of wet SiO2 (50% w/w) was used as an efficient nitrosating agent for the conversion of secondary amines to their corresponding nitroso compounds. N-Nitrosation reaction has been performed in dichloromethane at room temperature under mild and heterogeneous conditions. The reaction is operationally simple and corresponding products were achieved in good to excellent yields.

Keywords: Poly (N, N'-Dibromo-N-ethylene-benzene-1, 3-disulfonamide) [PBBS], N, N, N', N'-tetrabromobenzene-1, 3-disulfonamide [TBBDA], N-Nitrosation, N-Nitrosamines, Sodium nitrite, Wet SiO2

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Article Details

VOLUME: 10
ISSUE: 3
Year: 2013
Page: [204 - 208]
Pages: 5
DOI: 10.2174/1570178611310030011
Price: $58

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