Targeting Multiplicity: The Key Factor for Anti-Cancer Nanoparticles

Author(s): M. Gary-Bobo, O. Vaillant, M. Maynadier, I. Basile, A. Gallud, K. El Cheikh, E. Bouffard, A. Morere, X. Rebillard, P. Puche, P. Nirde, M. Garcia.

Journal Name: Current Medicinal Chemistry

Volume 20 , Issue 15 , 2013

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Abstract:

In this mini-review, we focus on different strategies to bring nanotools specifically to cancer cells. We discuss about a better targeting of tumor, combining the characteristics of tumor environment, the increase in nanoparticles life time, the biomarkers overexpressed on cancer cells and different physical methods for non invasive therapies. Here we detail the necessity of a synergy between passive and active targeting for an actual specificity of cancer cells.

Keywords: Cancer, multiple targeting, nanoparticles, non-invasive therapies

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Article Details

VOLUME: 20
ISSUE: 15
Year: 2013
Page: [1946 - 1955]
Pages: 10
DOI: 10.2174/0929867311320150002
Price: $58

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