Heterocyclic compounds are of high importance in constructing active drug intermediates library. The
emergence of solid-phase and combinatorial chemistry has led to renewed interest in using organoselenium resins to
library drug-like production. In this mini review, we summarize the construction of heterocyclic compounds libraries such
as isoxazoles, oxadiazoles, triazoles, pyrimidines, pyrrolines, indolines, benzopyrans, furans etc. using organoselenium
resins. And it provided efficient and practical ways for the preparation of a variety of well-defined functional heterocyclic
compounds with the advantages of good yields, high purity, straightforward operations, broad range and high diversity of
the products, lack of odor, and good stability of the resins, all of these give expression to green chemistry.