Rapid and Efficient Synthesis of N-alkylbenzamides Under Microwave Irradiation

Author(s): Jan K. Cermak, Karel Kolar, Vladimir Cirkva.

Journal Name: Letters in Organic Chemistry

Volume 10 , Issue 2 , 2013

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Abstract:

The microwave-assisted synthesis of N-alkylbenzamides from benzoic acid and primary aliphatic amines has been developed under solvent-free conditions. The different solid catalysts have been investigated. The suggested synthesis is environmentally friendly and excellent yields (97 - 99 %) have been reached.

Keywords: Amino-de-hydroxylation, heterogenous catalyst, microporous materials, microwave assisted synthesis, Nalkylbenzamides, solvent-free reaction

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Article Details

VOLUME: 10
ISSUE: 2
Year: 2013
Page: [126 - 130]
Pages: 5
DOI: 10.2174/1570178611310020011

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