MAVS: A New Weapon in the Fight Against Viral Infections

Author(s): Jose A. Boga, Maria de Ona, Santiago Melon, Marta E. Alvarez-Arguelles, Ana Morilla, Ana Coto-Montes.

Journal Name: Recent Patents on Endocrine, Metabolic & Immune Drug Discovery (Under Re-organization)

Volume 7 , Issue 2 , 2013


In addition to their participation in metabolic processes and control of programmed cell death, the role of mitochondria as a fundamental hub for innate anti-viral immunity is now emerging. The participation of the mitochondrial antiviral signaling protein (MAVS) as a central regulator of a complex signaling cascade, which results in the induction of antiviral and inflammatory responses has been described. A patent based on this role of MAVS is highlighted in this review.

Keywords: Immunity, MAVS, mitochondria, viral infection

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Article Details

Year: 2013
Page: [115 - 119]
Pages: 5
DOI: 10.2174/1872214811307020004
Price: $58

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