Emerging Role of Colloidal Drug Delivery Systems (CDDS) in NSAID Topical Administration

Author(s): Carmelo Puglia, Giorgia Giusy Tirendi, Francesco Bonina.

Journal Name: Current Medicinal Chemistry

Volume 20 , Issue 14 , 2013

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Abstract:

NSAIDs are the most commonly prescribed category of drugs for the treatment of musculoskeletal pain and inflammation associated with many conditions. Topical administration of these drugs is always the best choice since adverse effects occur commonly with systemic NSAID therapy.

Colloidal drug delivery systems (CDDS) are interesting systems, which are able to improve the duration of drug residence in the skin and to allow an achievable drug sustained and controlled release compared to conventional topical formulations.

This review focuses on micro and nanoemulsions, vesicular carriers and nanoparticles as novel high efficiency delivery systems of NSAIDs in topical applications.

Keywords: Dermal, in vitro, in vivo, nanotechnology, NSAIDs, transdermal.

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Article Details

VOLUME: 20
ISSUE: 14
Year: 2013
Page: [1847 - 1857]
Pages: 11
DOI: 10.2174/0929867311320140004
Price: $58

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