Endocannabinoid hydrolases are nowadays increasingly considered as potential therapeutic targets for treating
several pathological states. So far, numerous classes of endocannabinoid hydrolase inhibitors have been described. We
herein review the medicinal chemistry of these inhibitors with a particular emphasis on the basis of their design, chemical
structure, structure-activity relationships, and inhibition mechanisms.
Keywords: Endocannabinoid hydrolases, inhibitors, design, chemical structures, inhibition mechanism, structure-activity relationships.
Rights & PermissionsPrintExport