Anthracyclines Still Prove Effective in Anticancer Therapy

Author(s): Mikolaj Piekarski, Anna Jelinska.

Journal Name: Mini-Reviews in Medicinal Chemistry

Volume 13 , Issue 5 , 2013

Become EABM
Become Reviewer

Abstract:

Present-day is developing in many fields. Many pathological processes are better understood, including carcinogenesis. Consequently, the failure of pharmacotherapy aimed at cancerous diseases is becoming explainable. At the same time, new anticancer drugs continue to be introduced. Anthracycline antibiotics are a well-known and widely used group of anticancer drugs. However, in addition to their efficiency they demonstrate severe side effects compounded by the appearance of resistant cells. Therefore, the search for new anthracycline derivatives with improved pharmacodynamic properties and fewer adverse effects is in progress, delivering promising results.

Keywords: Anthracycline antibiotics, drugs modifications, cancer, cardiotoxicity

Rights & PermissionsPrintExport Cite as

Article Details

VOLUME: 13
ISSUE: 5
Year: 2013
Page: [627 - 634]
Pages: 8
DOI: 10.2174/1389557511313050001
Price: $58

Article Metrics

PDF: 9