Current Cancer Drug Targets

Ruiwen Zhang 
Texas Tech University Health Sciences Center
1300 Coulter Drive
Amarillo, TX 79106
USA

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Current and Potential Treatments for Cervical Cancer

Author(s): Grace P.C. Yee, Paul de Souza, Levon M. Khachigian.

Abstract:

Cervical cancer is the third most common carcinoma in women worldwide. Despite increasing efforts to improve therapy in this disease, a significant proportion of women still die, mostly from recurrent or chemoresistant disease. This review discusses current treatments for early cervical cancer, advanced disease, and recurrent cervical cancer, and covers concurrent chemoradiation, neoadjuvant chemotherapy before surgery and radiation, single agent treatment, combination treatment, platinum-based and non-platinum based therapy. We also discuss promising therapeutic strategies for cervical cancer including targeted therapy, cell-based therapy, combined siRNA and chemotherapy, and immunotherapy.

Keywords: Cervical cancer, side-effects, targeted, therapy.

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Article Details

VOLUME: 13
ISSUE: 2
Year: 2013
Page: [205 - 220]
Pages: 16
DOI: 10.2174/1568009611313020009
Price: $58