Abstract
Ethnopharmacological relevance: In the traditional system of medicine, the plant Capparis decidua is well known for curing a variety of ailments such as toothache, cough, asthma, intermittent fever, rheumatism and inflammation.
Aim of the study: The aim of the current study was to isolate and characterize the constituent responsible for the antimicrobial activity of the ethanolic extract of C decidua.
Materials and methods: The isolated compound was extracted from ethanolic extract & characterized by spectroscopic methods. The antimicrobial activity of isolated compound was carried out against gram positive strains (S aureus, M luteus, B subtilus) and gram negative ones (P aeruginosa, E coli), and Fungi like C albicans and A niger by the cup-plate assay method and minimum inhibitory concentrations (MICs).
Results: The active principle Oleiyl glucoside (n-octadec-9-enyl- β-D- glucopyranoside) was isolated from the ethanolic extract. The MIC values of the compound against gram positive bacteria were 62.5μg/ml, 62.5 μg/ml, 125μg/ml and against gram negative ones 31.25μg/ml, 250μg/ml. The compound was found to be active against C albicans 250 μg/ml only.
Conclusions: The isolated compound Oleiyl glucoside showed moderate activity against bacteria and fungi.
Keywords: Capparis decidua, antibacterial, antifungal, oleiyl glucosides
The Natural Products Journal
Title:Antimicrobial Activity of Oleiyl Glucoside Isolated from the Traditional Medicinal Plant, Capparis decidua
Volume: 3 Issue: 1
Author(s): Sushila Rathee, Permender Rathee, Dharmender Rathee and Deepti Rathee
Affiliation:
Keywords: Capparis decidua, antibacterial, antifungal, oleiyl glucosides
Abstract: Ethnopharmacological relevance: In the traditional system of medicine, the plant Capparis decidua is well known for curing a variety of ailments such as toothache, cough, asthma, intermittent fever, rheumatism and inflammation.
Aim of the study: The aim of the current study was to isolate and characterize the constituent responsible for the antimicrobial activity of the ethanolic extract of C decidua.
Materials and methods: The isolated compound was extracted from ethanolic extract & characterized by spectroscopic methods. The antimicrobial activity of isolated compound was carried out against gram positive strains (S aureus, M luteus, B subtilus) and gram negative ones (P aeruginosa, E coli), and Fungi like C albicans and A niger by the cup-plate assay method and minimum inhibitory concentrations (MICs).
Results: The active principle Oleiyl glucoside (n-octadec-9-enyl- β-D- glucopyranoside) was isolated from the ethanolic extract. The MIC values of the compound against gram positive bacteria were 62.5μg/ml, 62.5 μg/ml, 125μg/ml and against gram negative ones 31.25μg/ml, 250μg/ml. The compound was found to be active against C albicans 250 μg/ml only.
Conclusions: The isolated compound Oleiyl glucoside showed moderate activity against bacteria and fungi.
Export Options
About this article
Cite this article as:
Rathee Sushila, Rathee Permender, Rathee Dharmender and Rathee Deepti, Antimicrobial Activity of Oleiyl Glucoside Isolated from the Traditional Medicinal Plant, Capparis decidua, The Natural Products Journal 2013; 3 (1) . https://dx.doi.org/10.2174/2210315511303010010
DOI https://dx.doi.org/10.2174/2210315511303010010 |
Print ISSN 2210-3155 |
Publisher Name Bentham Science Publisher |
Online ISSN 2210-3163 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Latest Updates in Dengue Fever Therapeutics: Natural, Marine and Synthetic Drugs
Current Medicinal Chemistry Biochanin A Ameliorates Ovalbumin-induced Airway Inflammation through Peroxisome Proliferator-Activated Receptor-Gamma in a Mouse Model
Endocrine, Metabolic & Immune Disorders - Drug Targets Mobile Phone Based Health Care Technology
Recent Patents on Biomedical Engineering (Discontinued) PLA2 Mediated Arachidonate Free Radicals: PLA2 Inhibition and Neutralization of Free Radicals by Anti-Oxidants – A New Role as Anti-Inflammatory Molecule
Current Topics in Medicinal Chemistry Allosteric Enhancers for A1 Adenosine Receptor
Mini-Reviews in Medicinal Chemistry Active Metabolites Resulting from Decarboxylation, Reduction and Ester Hydrolysis of Parent Drugs
Current Drug Metabolism Gene and Gene-Environment Risk Factors in Sudden Undexpected Death in Infants
Current Pediatric Reviews Inhaled Corticosteroids in COPD: Pros and Cons
Current Drug Targets Exploring Pharmacological Significance of Chalcone Scaffold: A Review
Current Medicinal Chemistry Subclassification and Nomenclature of α- and β-Adrenoceptors
Current Topics in Medicinal Chemistry Impact of Inhaled Corticosteroids on the Natural History of Asthma in Children
Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry Regulation and Function of Antimicrobial Peptides in Immunity and Diseases of the Lung
Protein & Peptide Letters Adverse Drug Reactions and Safety Considerations of NSAIDs: Clinical Analysis
Current Drug Safety The Effect of Natural Soluble Polysaccharides on the Type 2 Diabetes through Modulating Gut Microbiota: A Review
Current Medicinal Chemistry The Therapeutic Index of Locally Acting Inhaled Drugs as a Function of their Fine Particle Mass and Particle Size Distribution – A Literature Review
Current Drug Delivery Surfactant Protein (SP)-A and SP-D as Antimicrobial and Immunotherapeutic Agents
Recent Patents on Anti-Infective Drug Discovery Use of Systemic Proteasome Inhibition as an Immune-Modulating Agent in Disease
Endocrine, Metabolic & Immune Disorders - Drug Targets Development of Dehydration-Rehydration Liposomal System Using Film Hydration Technique Followed by Sonication
Current Drug Delivery Vascular Remodelling and Angiogenesis in Asthma: Morphological Aspects and Pharmacological Modulation
Inflammation & Allergy - Drug Targets (Discontinued) Role of α- and β-adrenergic Mechanisms in the Pathogenesis of Pulmonary Injuries Characterized by Edema, Inflammation and Fibrosis
Cardiovascular & Hematological Disorders-Drug Targets