Capillary Electrophoresis with Mass Spectrometry: Applications to Metabolomic Analysis

Author(s): Katie Yan, Jeffrey Brumbaugh, Jeremy Barrett, Sarah Jung, Shen Hu.

Journal Name: Current Metabolomics

Volume 1 , Issue 2 , 2013

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Abstract:

The use of capillary electrophoresis with mass spectrometry (CE-MS) for metabolomic analysis has substantially increased in recent years. This hyphenated technique takes full advantage of the high separation efficiency of CE and the identification capability of MS, providing a powerful tool for rapid analysis and identification of metabolites in complex biological samples. This article focuses on an overview of some recent applications of CE-MS in metabolomics studies. We also discuss the techniques for the coupling of CE with MS and the potential of 2-D CE-MS for metabolomic analysis.

Keywords: CE-MS, 2-D CE, metabolomics.

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Article Details

VOLUME: 1
ISSUE: 2
Year: 2013
Page: [121 - 127]
Pages: 7
DOI: 10.2174/2213235X11301020002

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