Copper Exchanged SiO2/Al2O3 Catalyst Prepared by Sol-Gel Method for Intermolecular Hydroamination of Terminal Alkynes
Swati L. Pandhare,
Trupti V. Kotbagi,
Mohan K. Dongare,
Shubhangi B. Umbarkar.
Catalytic hydroamination of terminal alkynes with amines is the most attractive C-N bond forming method. Intermolecular
hydroamination of terminal alkynes with aromatic amine has been carried out using Cu- exchanged
SiO2/Al2O3 as a heterogeneous catalyst. SiO2/Al2O3 with Si/Al ratio 12.5 has been prepared by novel sol-gel method using
tetraethyl orthosilicate and aluminium sec-butoxide as Si and Al precursors respectively. The catalyst has been extensively
characterized using various physicochemical and spectroscopic techniques viz., X-ray diffraction analysis, BET
surface area, NH3-TPD, FTIR of adsorbed pyridine and 29Si and 27Al NMR. The catalyst showed very high conversion up
to 97% and turnover number of 335 for intermolecular hydroamination of terminal alkynes with amines. The reaction proceeded
smoothly with highly selective Markonikov addition product.
Keywords: Hydroamination, intermolecular, Markonikov, terminal alkynes, aromatic amines, Cu-exchanged, sol-gel, silicaalumina
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