Abstract
In orthopaedic tissue engineering, scaffolds may be viewed as a substitute for the extra-cellular matrix. Factors that contribute to an ideal scaffold include strength, degradation rate, porosity, surface property and immune response. Scaffolds may be composed of natural or synthetic polymers, each with its advantages and disadvantages. Composite scaffolds are utilised to alleviate the inherent issues with natural polymers whilst maintaining its benefits as well. This article reviews biomaterials and scaffolds in orthopaedic tissue engineering and covers clinical applications of scaffolds with particular emphasis on bone and cartilage tissue engineering.
Keywords: Biomaterials, orthopaedics, scaffolds, tissue engineering
Current Stem Cell Research & Therapy
Title:Biomaterials and Scaffolds in Bone and Musculoskeletal Engineering
Volume: 8 Issue: 3
Author(s): Dennis Kosuge, Wasim S. Khan, Behrooz Haddad and David Marsh
Affiliation:
Keywords: Biomaterials, orthopaedics, scaffolds, tissue engineering
Abstract: In orthopaedic tissue engineering, scaffolds may be viewed as a substitute for the extra-cellular matrix. Factors that contribute to an ideal scaffold include strength, degradation rate, porosity, surface property and immune response. Scaffolds may be composed of natural or synthetic polymers, each with its advantages and disadvantages. Composite scaffolds are utilised to alleviate the inherent issues with natural polymers whilst maintaining its benefits as well. This article reviews biomaterials and scaffolds in orthopaedic tissue engineering and covers clinical applications of scaffolds with particular emphasis on bone and cartilage tissue engineering.
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Cite this article as:
Kosuge Dennis, S. Khan Wasim, Haddad Behrooz and Marsh David, Biomaterials and Scaffolds in Bone and Musculoskeletal Engineering, Current Stem Cell Research & Therapy 2013; 8 (3) . https://dx.doi.org/10.2174/1574888X11308030002
DOI https://dx.doi.org/10.2174/1574888X11308030002 |
Print ISSN 1574-888X |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-3946 |
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