J-TM Align: Efficient Comparison of Protein Structure Based on TMAlign
Pietro H. Guzzi,
Proteins interact among them and different interactions are represented as graphs named Protein to Protein
Interaction (PPI) networks. From a physical point of view, interactions are performed by contacts among protein structure.
Consequently, the study and the comparison of protein structure is an important field in Bioinformatics and
Computational Biology. The TM-Align algorithm is a method that presents one of the best performance but is currently
available only as a stand alone application with a simple command-line interface available only on Linux platforms. We
provide a comprehensive tool, (J-TMAlign) allowing a graphical, easy to use, interface to access J-TMAlign functions and
the possibility to visualize compared structure. Finally, J-TMAlign is based on a multi-threaded architecture enables user
to submit multiple jobs that are executed in a concurrent and time-efficient way.
Keywords: Distributed processing, docking, multithreads, protein analysis, protein structure comparison, protein structure, wrappers, eukaryotic systems, Docking Algorithms, Fold Prediction Algorithms, JProt Align
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