Abstract
Recently ZnO quantum dots are reported to be very promising for drug delivery. It has also been reported that adsorptive material can deliver drug molecules by simple adsorption and they release the drug at site of action by subsequent desorption. This has been shown for carbon nanotubes and some other hydrophobic molecules for transdermal applications in the literature. Therefore it was aimed to find the effect of ZnO quantum dots on transdermal penetrations of selected model drug molecules (ketoprofen and dexketoperofen). Drug coated ZnO quantum dots were found to increase transdermal penetration of ketoprofen and dexketoprofen through rat skin.
Keywords: Dexketoprofen, ketoprofen, kuantum dots, penetration, transdermal, ZnO
Current Drug Delivery
Title:Cheap, Suitable, Predictable and Manageable Nanoparticles for Drug Delivery: Quantum Dots
Volume: 10 Issue: 1
Author(s): Ismail Tuncer Degim and Demet Kadioglu
Affiliation:
Keywords: Dexketoprofen, ketoprofen, kuantum dots, penetration, transdermal, ZnO
Abstract: Recently ZnO quantum dots are reported to be very promising for drug delivery. It has also been reported that adsorptive material can deliver drug molecules by simple adsorption and they release the drug at site of action by subsequent desorption. This has been shown for carbon nanotubes and some other hydrophobic molecules for transdermal applications in the literature. Therefore it was aimed to find the effect of ZnO quantum dots on transdermal penetrations of selected model drug molecules (ketoprofen and dexketoperofen). Drug coated ZnO quantum dots were found to increase transdermal penetration of ketoprofen and dexketoprofen through rat skin.
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Cite this article as:
Tuncer Degim Ismail and Kadioglu Demet, Cheap, Suitable, Predictable and Manageable Nanoparticles for Drug Delivery: Quantum Dots, Current Drug Delivery 2013; 10 (1) . https://dx.doi.org/10.2174/1567201811310010006
DOI https://dx.doi.org/10.2174/1567201811310010006 |
Print ISSN 1567-2018 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5704 |
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