Recently ZnO quantum dots are reported to be very promising for drug delivery. It has also been reported that
adsorptive material can deliver drug molecules by simple adsorption and they release the drug at site of action by subsequent
desorption. This has been shown for carbon nanotubes and some other hydrophobic molecules for transdermal applications
in the literature. Therefore it was aimed to find the effect of ZnO quantum dots on transdermal penetrations of
selected model drug molecules (ketoprofen and dexketoperofen). Drug coated ZnO quantum dots were found to increase
transdermal penetration of ketoprofen and dexketoprofen through rat skin.
Keywords: Dexketoprofen, ketoprofen, kuantum dots, penetration, transdermal, ZnO
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