An Efficiently Sonochemical Synthesis of Novel Pyrazoles, Bipyrazoles and Pyrazol-3- ylPyrazolo[3,4-d]pyrimidines Incorporating 1H-benzoimidazole Moiety

Author(s): Nesreen S. Ahmed, Tamer S. Saleh, El-Sayed H. El-Mossalamy.

Journal Name: Current Organic Chemistry

Volume 17 , Issue 2 , 2013

Become EABM
Become Reviewer

Abstract:

Novel pyrazoles, bipyrazoles and pyrazol-3-ylpyrazolo[3,4-d]pyrimidines were synthesized using the versatil synthon 2-(1Hbenzimidazol- 2-yl)-3,3-bis(methylthio) acrylonitrile (1). Reactions were carried out under silent and ultrasonic conditions. In general, improvement in rates and yields were observed when reactions were carried out under ultrasonic irradiation compared with silent condition. Structures of the products were established on analytical and spectral data.

Keywords: Pyrazoles, Bipyrazoles, Benzimidazole, Ultrasonic irradiation, Pyrazolo[3, 4-d]pyrimidine

Rights & PermissionsPrintExport Cite as


Article Details

VOLUME: 17
ISSUE: 2
Year: 2013
Page: [194 - 202]
Pages: 9
DOI: 10.2174/1385272811317020016
Price: $58

Article Metrics

PDF: 2