Aim: In this paper, we provide an update on the conceptual issues of psychiatric neuroimaging, especially in the
light of the current reductive claims of the eliminative physicalism.
Argument: our argument is developed on three stages. The first is to highlight the crucial importance of phenomenological
psychopathology and person-centered approach, which remains underestimated; the second is to bring forward the view
that functional neuroimaging is relevant to the area of ‘translation’ in the mind-brain debate. The third point is to present a
critical analysis of the shortcomings in structural and functional neuroimaging from methodological and epistemological
Conclusion: a novel paradigm for translational cross-validation among neuroscience, psychopathology and clinical psychology