A convenient method for the synthesis of organic carbamates of 2-aminopyridine without using hazardous
chloroformate reagent is developed. This alternate approach for the synthesis of organic carbamates and their alkylation to
2-alkylaminopyridines is more practical and economical to be used on large scale. The amazing behavior of 2-
aminopyridine helps in forming organic carbamates unlike 3-aminopyridine and 4-aminopyridine.
Keywords: Alkylation, alkyl aminopyridine, 2-aminopyridine, Boc anhydride, carbamates, prodrugs, maytansine, alkylation, toxic, economical method, chemicals
Rights & PermissionsPrintExport