Eight dendritic polyphenols (generation1) of hydroxy benzoic and hydroxy cinnamic acids were synthesized in
good overall yields using Mitsunobu reaction and BOP coupling agent and their antioxidant activities including radical
scavenging activity were studied by cyclic voltammetry. Antioxidants with strong free radical scavenging abilities and
devoid of prooxidant effects would be of immense biological importance. Therefore to minimize prooxidant effects and to
increase free radical quenching properties, the dendrimers were designed with metal chelating compounds as core and
with a periphery, rich in phenolic hydroxyl groups, benzylic hydrogens and electron donating ring substituents.
Keywords: Antioxidant activity, BOP, cyclic voltammetry(CV), dendritic polyphenols, Mitsunobu reaction, polyphenols, antioxidant, oligomers, dendrimers, Mass spectra
Rights & PermissionsPrintExport