A One-Pot Multi-Component Synthesis of N-cyclohexyl-3-arylquinoxaline- 2-amines Using ZnO Nanoparticles as a Heterogeneous Reusable Catalyst

Author(s): Abolfazl Ziarati , Javad Safaei-Ghomi , Sahar Rohani .

Journal Name: Letters in Organic Chemistry

Volume 10 , Issue 1 , 2013

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A general synthetic route to synthesis of N-cyclohexyl-3-aryl-quinoxaline-2-amines has been developed using ZnO nanoparticles under mild conditions. The multi-component reactions of aldehydes, o-phenylenediamine and cyclohexyl isocyanide were carried out to afford some N-cyclohexyl-3-aryl-quinoxaline-2-amines derivatives. The present approach offers several advantages such as high yields, environmentally benign, easy purification, recovery and reusability of the catalyst.

Keywords: N-cyclohexyl-3-aryl-quinoxaline-2-amines, ZnO nanoparticles, heterogeneous catalyst, multi-component, isocyanides, reagent, toluene, diffraction peak, purity, SEM image

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Article Details

Year: 2013
Page: [47 - 52]
Pages: 6
DOI: 10.2174/1570178611310010012

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PDF: 15