Benzimidazole Derivatives as Potential Anticancer Agents

Author(s): Ahmed A. El Rashedy , Hassan Y. Aboul-Enein .

Journal Name: Mini-Reviews in Medicinal Chemistry

Volume 13 , Issue 3 , 2013

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Abstract:

Benzimidazole ring system is found in many bioactive heterocyclic compounds because of their diverse biological and clinical applications. Furthermore, benzimidazole derivatives are structural isosters of naturally occurring nucleotides, thus they can interact with biological macromolecules such as proteins, enzymes and receptors. This review discusses the benzimidazole derivatives which possess anticancer activity of medicinal efficacy.

Keywords: Substituted Benzimidazoles, anticancer activity

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Article Details

VOLUME: 13
ISSUE: 3
Year: 2013
Page: [399 - 407]
Pages: 9
DOI: 10.2174/1389557511313030008
Price: $58

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