Letters in Drug Design & Discovery

G. Perry
University of Texas
San Antonio, TX
USA
Email: lddd@benthamscience.org

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PEG-600 Mediated Facile and Green Synthesis of Novel Imide Derivatives and Their Biological Activity Evaluation

Author(s): Yervala Dathu Reddy, Padam Praveen Kumar, Bhoomireddy Rama Devi, Pramod Kumar Dubey, Yalamanchili Bharathi Kumari.

Abstract:

Facile and green syntheses of novel 2-(1,2-benzisothiazole-3-one-1,1-dioxide)-N-arylacetamides, 2-(1,3- dioxoisoindolin-2-yl)-N-arylacetamides and 2-(N-(2-oxo-2-(arylamino)ethyl)sulfamoyl (or) carbamoyl)benzoic acids have been developed and tested for their biological activities against Baccilus megaterieum, Escherichia coli, Providencia stuartii, Pseudomonas putida. Some of the synthesized compounds possess good activity against Escherichia coli and Baccilus megaterieum compared to standard drugs.

Keywords: Environmental sustainable synthesis; Antibacterial activity; Sodium salt of saccharin; Potassium salt of phthalimide.

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Article Details

VOLUME: 10
ISSUE: 3
Year: 2013
Page: [226 - 238]
Pages: 13
DOI: 10.2174/1570180811310030006
Price: $58