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Nanotechnology-Based Drug Delivery Systems for Treatment of Hyperproliferative Skin Diseases - A Review

Author(s): Fernanda Kolenyak dos Santos, Marcia Helena Oyafuso, Charlene Priscila Kiill, Maria Palmira Daflon- Gremiao, Marlus Chorilli.

Abstract:

The chronic hyperproliferative diseases (CHD) include cancer, precancerous lesions and diseases of unknown etiology such as psoriasis. Various drugs have been used in the treatment of CHD, such as antiproliferative and corticosteroids in general. However, some drugs have properties that limit their effectiveness, such as low solubility in water and low penetration of the skin. Thus, the control of drug release in the skin may improve efficacy and reduce side effects of many drugs used in hyperproliferative diseases. The purpose of this study was to make a systematic review of nanotechnology-based drug delivery systems used against hyperproliferative skin diseases.

Keywords: Chronic hyperoproliferative diseases, drug delivery systems, nanotechnology, skin diseases, skin treatment, skin cancer, psoriasis

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Article Details

VOLUME: 9
ISSUE: 1
Year: 2013
Page: [159 - 167]
Pages: 9
DOI: 10.2174/1573413711309010027