Abstract
The chitosan (CS)-organic rectorite (OREC) composites are prepared with the method of solution intercalation. Electrospun nanofibrous mats are made from intercalated CS-OREC composites at different mass ratios. The properties and structure of intercalated CS-OREC can be verified by small angle X-ray diffraction (SAXRD) and transmission electron microscopy (TEM) micrographs. Energy dispersive X-ray (EDX) spectroscopy and fourier transform infrared (FT-IR) spectra reveal that OREC presents in the composite nanofibrous mats. The MTT assay indicates that the cytotoxicity of the intercalated CS-OREC nanofibrous mats is low. Besides, the content of OREC in nanofibrous mats has a significant influence on the viability of cells. Antibacterial test confirms that OREC can increase the inhibition rate of the nanofibrous mats against Escherichia coli.
Keywords: Antibacterial activity, bacterial activity, cytotoxicity, chitosan, electrospinning, intercalation, organic rectorite
Current Nanoscience
Title:Cytotoxicity and Antibacterial Activity of Chitosan-organic Rectorite Intercalated Nanofibrous Mats
Volume: 9 Issue: 1
Author(s): Jing Du, Xueyong Li, Chen Yang, Wei Li, Weijuan Huang, Rong Huang, Xue Zhou and Hongbing Deng
Affiliation:
Keywords: Antibacterial activity, bacterial activity, cytotoxicity, chitosan, electrospinning, intercalation, organic rectorite
Abstract: The chitosan (CS)-organic rectorite (OREC) composites are prepared with the method of solution intercalation. Electrospun nanofibrous mats are made from intercalated CS-OREC composites at different mass ratios. The properties and structure of intercalated CS-OREC can be verified by small angle X-ray diffraction (SAXRD) and transmission electron microscopy (TEM) micrographs. Energy dispersive X-ray (EDX) spectroscopy and fourier transform infrared (FT-IR) spectra reveal that OREC presents in the composite nanofibrous mats. The MTT assay indicates that the cytotoxicity of the intercalated CS-OREC nanofibrous mats is low. Besides, the content of OREC in nanofibrous mats has a significant influence on the viability of cells. Antibacterial test confirms that OREC can increase the inhibition rate of the nanofibrous mats against Escherichia coli.
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Cite this article as:
Du Jing, Li Xueyong, Yang Chen, Li Wei, Huang Weijuan, Huang Rong, Zhou Xue and Deng Hongbing, Cytotoxicity and Antibacterial Activity of Chitosan-organic Rectorite Intercalated Nanofibrous Mats, Current Nanoscience 2013; 9 (1) . https://dx.doi.org/10.2174/1573413711309010004
DOI https://dx.doi.org/10.2174/1573413711309010004 |
Print ISSN 1573-4137 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6786 |
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