Adnexal Mass and Ovarian Cancer in Menopause
Pp. 315-325 (11)
Tanja Pejovic and Farr Nezhat
The differential diagnosis of the adnexal mass indeed varies with the age.
Age is the most important factor in determining the potential for malignancy. In
postmenopausal women, an adnexal mass should be considered highly abnormal and
must be promptly evaluated. The risk of malignancy in this age group is increased from
13% in premenopausal to 45% in postmenopausal women, however 55% of
postmenopausal women with palpable ovaries do have a benign tumor. The most
common ovarian tumors in this age group include epithelial ovarian tumors followed by
stromal tumors and sex-cord tumors. The standard operative approach to adnexal
masses in postmenopausal women has been explorative laparotomy to ensure adequate
exposure for the treatment of ovarian cancer. However, laparoscopic evaluation of
suspicious adnexal masses is considered a reasonable approach with ability to perform
frozen section histologic analysis and confirm to laparotomy if needed.
Menopause, Ovarian Cancer, Ovarian Surface Epithelium, Adnexal
Mass, Laparoscopy, CA125, Endometriosis.
Oregon Health & Science University, Portland, Oregon, USA