Biomarkers for Cancers in Women: Present Status and Future Perspectives
Tarala D. Nandedkar.
In women breast, ovarian, endometrial and cervical are cancers require attention due to high morbidity and
mortality. Although the percentage is high in elderly women, even the younger generation can be affected. Early diagnosis
can be of great advantage in increasing the survival rate. Newer markers are being reported in recent years based on
expression of genetic and epigenetic alterations. Research on involvement of miRNAs in various cancers including those
in women has suggested a number of biomarkers for early diagnosis. However, their validation is essential prior to clinical
application. Attention has also been focused on cancer stem cells so as to explore their application in diagnosis, prognosis
and possible therapy. Latest information in this area is reviewed here with the intention to disseminate the knowledge with
future path of research and necessity for more investigation.
Keywords: Epigenetic markers, miRNA, DNA methylation, cancer Stem cells, Biomarkers, Cancer, apoptosis, malignancy
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