Advances in Studies on the Rupestonic Acid Derivatives as Anti-influenza Agents

Author(s): Jianping Yong , Canzhong Lu , Haji Akber Aisa .

Journal Name: Mini-Reviews in Medicinal Chemistry

Volume 13 , Issue 2 , 2013

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Abstract:

Rupestonic acid (isolated from the Chinese traditional medicine Artemisia rupestris L.) is a sesquiterpene with multifunctional groups and possess higher activity against influenza virus B. In order to improve the biological activity of rupestonic acid, many derivatives have been synthesized and their anti-influenza activity was screened. This review describes the rupestonic acid derivatives and their anti-influenza activity studied by our researching group.

Keywords: Rupestonic acid derivatives, anti-influenza virus, structure-activity relationship

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Article Details

VOLUME: 13
ISSUE: 2
Year: 2013
Page: [310 - 315]
Pages: 6
DOI: 10.2174/1389557511313020012
Price: $58

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