Biological Activities and Corresponding SARs of Andrographolide and Its Derivatives

Author(s): Bin Zhou , Dayong Zhang , Xiaoming Wu .

Journal Name: Mini-Reviews in Medicinal Chemistry

Volume 13 , Issue 2 , 2013

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Abstract:

In recent years, pharmaceutical chemists have synthesized large numbers of andrographolide derivatives, which bear important biological activities such as anti-inflammatory, antibacterial, antivirus, antitumor, antidiabetic, and antifeedant. Consequently, corresponding SARs were increasingly obvious. This paper aimed to review all the available literature in this field, highlighting the significant achievements on the structural modification and SARs of andrographolide and its derivatives.

Keywords: Andrographolide derivatives, biological activities, SARs

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Article Details

VOLUME: 13
ISSUE: 2
Year: 2013
Page: [298 - 309]
Pages: 12
DOI: 10.2174/1389557511313020011
Price: $58

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