Synthesis of Trifluoromethyl-Substituted Fused Bicyclic Heterocycles and their Corresponding Benzo-Fused Analogues
Pp. 409-455 (47)
Ahmed H. M. Elwahy and Mohamed R. Shaaban
Development of efficient routes to many kinds of fluorine-containing
heterocycles is an attractive area of research since these compounds are now widely
recognized as important organic materials for their potential use in medicinal and
agricultural scientific fields. This review survey research works on trifluoromethylsubstituted
fused bicyclic heterocycles and their corresponding benzo-fused analogues over
the last twelve years. Different approaches for the synthesis of such systems are discussed.
Organofluorine, trifluoromethyl, bicyclic fused heterocycles, fused
pyrroles, fused thiadiazoles, fused pyrazines, fused phthalazines, fused pyridines,
fused pyrimidines, fused pyridazines, fused triazines, fused tetrazines, fused
benzimidazoles, fused triazoles, fused pyrazoles, fused isoxazoles, fused pyrans,
fused chromenes, fused naphthyridines, fused diazepines.
Department of Chemistry, Cairo university, Giza, Egypt