Palladium-Catalyzed Cycloaddition of 1,3-Butadiynes with Water: An Alternative Efficient Catalytic System for Atom-Economic Synthesis of 2,5-Disubstituted Furans

Author(s): Qingwei Zheng, Ruimao Hua, Tao Yin.

Journal Name: Current Organic Synthesis

Volume 10 , Issue 1 , 2013

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Abstract:

An efficient Pd(PPh3)4/2,5-norbornadiene-catalyzed cycloaddition of 1,4-disubstituted 1,3-butadiynes with H2O under basic conditions for straightforward and simple synthesis of 2,5-disubstituted furans is described.

Keywords: Cycloaddition, 1, 3-butadiynes, furan derivative, palladium, water

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Article Details

VOLUME: 10
ISSUE: 1
Year: 2013
Page: [161 - 164]
Pages: 4
DOI: 10.2174/1570179411310010007

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