A new, efficient, and solvent-free cyclocondensation reaction of arylmethylidenepyruvic acids with 6-
aminouracils is presented that uses a catalytic amount of ZnO nanoparticles (ZnO Nps) as a recyclable catalyst at 70 °C.
This protocol has the advantages of high yields (91-98%), easy work-up, very short reaction time (2 h), and using
environmentally friendly procedure.
Keywords: Cyclocondensation, heterogeneous catalyst, solvent-free, ZnO nanoparticles, recyclable catalyst, metal oxide, solvent-free.
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