The catalytic property of Cu(II) Schiff-base complex in an efficient synthesis of 1,8-dioxodecahydroacridines
was investigated. The one-pot three component reaction of dimedone, aromatic aldehydes and aromatic amines or
ammonium acetate in water afforded the corresponding 1,8-dioxodecahydroacridines with excellent yields. This reaction
was carried out in the presence of 1 mol% of catalysts at room temperature. The reusability of the catalysts was
demonstrated by a five-run test without loss of its activity. Also, this catalyst possesses several advantages including mild
reaction conditions, lower catalytic loading, shorter reaction times, high yield of the products, inexpensive and cleaner
(Green chemistry) reactions.
Keywords: 1, 8-Dioxodecahydroacridine, Cu(II) Schiff-base catalyst, multi component reaction, one-pot synthesis, water
solvent, water, Green chemistry, Acridine, green catalysts, polar solvents.
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