Recent Patents on Drug Delivery & Formulation

Ryan F. Donnelly
School of Pharmacy
Queen's University Belfast
Belfast
UK

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Stem Cell Technologies Based on Hemangioblast Technology Focusing on Human Blood Cells

Author(s): Laura Forte and Anna C. Berardi

Affiliation: Laboratory of Stem Cells, Department of Transfusion Medicine, Pescara Spirito Santo Hospital, Via Fonte Romana 8, 65125 Pescara, Italy.

Keywords: Hematopoietic stem cells, hemangioblast-based methods, stem cell technologies

Abstract:

The in vitro generation of hematopoietic stem cells (HSCs) and mature hematopoietic cells from hemangioblast derived from embryonic stem (ES) or induced pluripotent stem (iPS) cells promises to provide an alternative source of cells that could replace total bone marrow cells or HSC-enriched fractions. This mini-review deals with innovation related to hemangioblast-based methods for blood cells production as disclosed in recent patent literature and current barriers to clinical translation are discussed.

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Article Details

VOLUME: 7
ISSUE: 1
Page: [4 - 8]
Pages: 5
DOI: 10.2174/1872211311307010003