Blood Pressure Variability and Mortality in end Stage Renal Disease
Maria L. Sirico,
Lucia Di Micco,
Biagio Di Iorio.
Blood pressure (BP) measurement is a simple, and reproducible methool and is easily accepted by patients. It is
well known that in a single subject BP may change during the day; this fact is considered physiological by many
physicians and does not influence the final estimated value of BP. However, it’s reasonable to suppose that blood pressure
variability (BPV) has clinical consequences and that exists a cardiovascular risk related to it. In fact, recent observations
indicate that BP variations could be responsible for organ damage associated with hypertension more than the systolic and
In this study, we aim to analyze and compare published data in literature concerning the presumable correlations between
BP variability and outcomes, both in Chronic Kidney Disease (CKD) and End stage Renal Disease (ESRD). We conclude
that BPV represents an important cardiovascular risk factor for both patients with CKD and for those in dialysis. No
correlations were found between BPV and the progression of CKD. However, this is a retrospective study and more
(RCTS) are needed on this topic.
Keywords: Randomized controlled trials, blood pressure, end stage rental disease
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