Infection with Human Immunodeficiency Virus (HIV) remains a global public health problem. Although the epidemic has not
been completely controlled, there was considerable progress in HIV prevention and treatment during the last 30 years. The modern prevention
approaches are multi-component including also the administration of combinations of potent antiretroviral agents as a prophylaxis
after occupational or non-occupational exposures to HIV. The aim of the current review is to present the chemical and pharmacological
characteristics of antiretroviral drugs used in HIV prophylaxis and to describe briefly the medical management of exposures to potentially
infectious body fluids.
Keywords: HIV, prophylaxis, antiretrovirals, exposure, occupational, non-occupational
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