Antiretrovirals for HIV Exposure Prophylaxis

Author(s): G. Nikolopoulos, S. Tsiodras, S. Bonovas, A. Hatzakis.

Journal Name: Current Medicinal Chemistry

Volume 19 , Issue 35 , 2012


Abstract:

Infection with Human Immunodeficiency Virus (HIV) remains a global public health problem. Although the epidemic has not been completely controlled, there was considerable progress in HIV prevention and treatment during the last 30 years. The modern prevention approaches are multi-component including also the administration of combinations of potent antiretroviral agents as a prophylaxis after occupational or non-occupational exposures to HIV. The aim of the current review is to present the chemical and pharmacological characteristics of antiretroviral drugs used in HIV prophylaxis and to describe briefly the medical management of exposures to potentially infectious body fluids.

Keywords: HIV, prophylaxis, antiretrovirals, exposure, occupational, non-occupational

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Article Details

VOLUME: 19
ISSUE: 35
Year: 2012
Page: [5924 - 5939]
Pages: 16
DOI: 10.2174/0929867311209065924
Price: $65

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