Recent Developments and Patents on Biological Sensing using Nanoparticles in Microfluidic Systems
Kin Fong Lei
Affiliation: Engineering Building, Chang Gung University, 259 Wen-Hwa 1st Road, Kwei-Shan, Tao-Yuan, 333 Taiwan, R.O.C.
Keywords: Microfluidics, Microfluidic systems, Lab-on-chip, Nanoparticles, Biological sensing
Microfluidic systems provide a total solution of biological and chemical analysis from the sample application to
the display of the analysis results. A lot of developments on the point-of-care diagnostic applications have been reported
and the commercial possibility is shown. To achieve sensitive and specific biological sensing, nanoparticles may provide a
promising tool because they have similar length scale with the biomolecules. The nano-sensing technology suggests a molecular
level detection of the biomolecules to pursue higher performance. In this review, recent developments and patents
on the biological sensing using nanoparticles in microfluidic systems are discussed. An updated, systematic and rapid reference
in the field of nano-biological sensing is provided.
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