Nonfatal Suicidal Overdose of Olanzapine in an Adolescent

Title:Nonfatal Suicidal Overdose of Olanzapine in an Adolescent

Volume: 7 Issue: 4

Author(s): Lokesh Kumar Singh, Samir Kumar Praharaj and Manoj Sahu

Affiliation:

Keywords: Olanzapine, overdose, adolescent DSH, Nonfatal Suicidal Overdose, atypical antipsychotic, thienobenzodiazepine, pharmacological actions, somnolence, mydriasis, blurred vision

Abstract: The atypical antipsychotic olanzapine is increasingly being used for various psychiatric conditions. There are few reports of olanzapine overdose in adolescent population. We report a case of 16-year-old adolescent who ingested 750 mg olanzapine, the highest reported nonlethal dose of olanzapine in adolescents. He presented with tachycardia, hypotension, generalized myoclonus, hyperpyrexia, muscular rigidity, leukocytosis and elevated creatine phosphokinase (CPK) levels. He recovered from the toxicity with minimal intervention.

Cite this article as:

Kumar Singh Lokesh, Kumar Praharaj Samir and Sahu Manoj, Nonfatal Suicidal Overdose of Olanzapine in an Adolescent, Current Drug Safety 2012; 7 (4) . https://dx.doi.org/10.2174/157488612804096605