Organic Domino Reactions Catalyzed by Molecular Iodine
Gunasekar Ramachandran and Kulathu I. Sathiyanarayanan
Affiliation: Chemistry Division, School of Advanced Sciences, VIT University, Vellore-632014, Tamilnadu India.
Molecular iodine has established itself as an efficient catalyst in organic synthesis to attain several organic
transformations. Domino reactions involve the synthesis of a target molecule in a single step where three or more components
are reacting simultaneously. Thus these types of domino reactions are carried out in the presence of iodine as a catalyst.
They have more significance and are fascinating in organic synthesis. The use of molecular iodine as catalyst in various
domino reactions along with the recent patents is discussed in this review.
Keywords: Biginelli reaction, domino reaction, imino-Diels-Alder (Povarov) reaction, Mannich reaction, Michael reaction and
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