Recent Patents on Inflammation & Allergy Drug Discovery

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Effects of Amine Oxidases in Allergic and Histamine-Mediated Conditions

Author(s): Bruno Mondovi, Wieslawa A. Fogel, Rodolfo Federico, Carmen Calinescu, Mircea A. Mateescu, Arianna C. Rosa and Emanuela Masini

Affiliation: Department of Biochemical Sciences A. Rossi Fanelli, University of Rome Sapienza, Rome, Italy.

Keywords: Amine oxidase, anaphylaxis, bowel diseases, cell proliferation, diabetes, histamine, inflammation, ischemiareperfusion, polyamines, food histaminosis

Abstract:

This review provides an update on histamine, on diamine oxidase (DAO) and on their implications in allergy and various conditions or affections, such as food histaminosis, ischemia and inflammatory bowel diseases (IBD). The review also presents, in brief, patent coverage on therapies for allergy and IBD with the focus on histamine-related treatments.

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Article Details

VOLUME: 7
ISSUE: 1
Page: [20 - 34]
Pages: 15
DOI: 10.2174/1872213X11307010020