Comparative Genomics and Systems Biology of Malaria Parasites Plasmodium
Malaria is a serious infectious disease that causes over one million deaths yearly. It is caused by a group of
protozoan parasites in the genus Plasmodium. No effective vaccine is currently available and the elevated levels of
resistance to drugs in use underscore the pressing need for novel antimalarial targets. In this review, we survey omics
centered developments in Plasmodium biology, which have set the stage for a quantum leap in our understanding of the
fundamental processes of the parasite life cycle and mechanisms of drug resistance and immune evasion.
Keywords: Drug, genomics, interactome, malaria, plasmodium, proteomics, systems biology, transcriptomics, vaccine
Rights & PermissionsPrintExport