We have developed a new combination of catalyst system for the synthesis of N-(p-benzoylaminoaryl)-N'-Boc
piperazines under microwave conditions (Biotage, 300 Watt) in the presence of sodium tert-butoxide and in DMF. The
catalyst and ligand used are Tris (dibenzylideneacetone) dipalladium(0) and 2-Dicyclohexylphosphino-2-(N,Ndimethylamino)
biphenyl (Dave Phos) respectively, the desired N-(p-benzoylaminoaryl)-N'-Boc Piperazines was obtained
in good yields (80-92%).