Abstract
An efficient and regioselective one-pot direct synthesis of 4-vinyl-1,2,3-triazoles via cycloaddition of azides with propargyl alcohols and dehydration catalyzed by a CuCl/RuCl3·3H2O bimetallic catalysts in the presence of TFA (Trifluoroacetic acid) is developed.
Keywords: Azides, Cuprous chloride, Propargyl alcohols, Ruthenium trichloride hydrate, 4-Vinyl-1, 2, 3-triazoles, Trifluoroacetic acid.
Call for Papers in Thematic Issues
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Organic synthesis is a fundamental discipline in chemistry, crucial for the creation of complex molecules with diverse applications in pharmaceuticals, materials science, and beyond. However, the process of designing efficient synthetic routes for target molecules remains challenging. Chemical graph theory, a branch of theoretical chemistry, offers powerful tools for understanding ...read more
Photoswitches for Molecular Recognition
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