Vinyl and aryl sulfonates are ubiquitous building blocks in organic chemistry, frequently exploited in the total synthesis of
natural and non-natural products, due to their ease of formation and to their high reactivity, especially in metal-catalyzed cross-coupling
reactions. The present review thus aims at first describing the classical and current methods to prepare these valuable synthons, with an
emphasis on reaction mechanisms. The second part of the review aims at highlighting their main applications in organic synthesis, especially
in the course of natural product total syntheses.
Keywords: Vinyl sulfonates, cross-coupling, elimination, substitution, synthesis, natural products.
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