Phytoconstituents of Phlogacanthus pubinervius Nees: Leaves and their free Radical Scavenging Activities

Author(s): Warjeet S. Laitonjam, Rajkumar S. Yumnam, Brajeshwari D. Kongbrailatpam.

Journal Name: The Natural Products Journal

Volume 2 , Issue 4 , 2012

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Investigation on the secondary metabolites of the leaves of Phlogacanthus pubinervius Nees. led to the isolation of a new terpenoidal glycoside, 3-O-[ß-D-glucopyranosyl-(1’2’)--L-rhamnopyranosylphlogaca-nthoside], 5 along with five other compounds including -sitosterol (1), -sitosterol-D-glucoside (2), Stigmasta-5,22-dien-7-on-3ß-ol (3), 19-hydroxy- phlogacantholide (4), and (2E,7Z)-2,6-dihydroxycycloocta-2,7-dienone (6). The structures of the compounds (1-6) were established by physical and spectroscopic analysis. Free radical scavenging activities of the isolates were evaluated by using 1,1-diphenyl-2-picrylhydrazyl (DPPH) method and the Isosbestic points of the isolates were also reported.

Keywords: Phlogacanthus pubinervius, leaves, terpenoidal glycoside, free radical, scavenging, isosbestic point, phytoconstituent, metabolites, leaves, compound.

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Article Details

Year: 2012
Page: [287 - 292]
Pages: 6
DOI: 10.2174/2210315511202040287
Price: $58

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