Phytoconstituents of Phlogacanthus pubinervius Nees: Leaves and their free Radical Scavenging Activities
Warjeet S. Laitonjam,
Rajkumar S. Yumnam,
Brajeshwari D. Kongbrailatpam.
Investigation on the secondary metabolites of the leaves of Phlogacanthus pubinervius Nees. led to the
isolation of a new terpenoidal glycoside, 3-O-[ß-D-glucopyranosyl-(1’2’)--L-rhamnopyranosylphlogaca-nthoside],
5 along with five other compounds including -sitosterol (1), -sitosterol-D-glucoside (2), Stigmasta-5,22-dien-7-on-3ß-ol
(3), 19-hydroxy- phlogacantholide (4), and (2E,7Z)-2,6-dihydroxycycloocta-2,7-dienone (6). The structures of the
compounds (1-6) were established by physical and spectroscopic analysis. Free radical scavenging activities of the isolates
were evaluated by using 1,1-diphenyl-2-picrylhydrazyl (DPPH) method and the Isosbestic points of the isolates were also
Keywords: Phlogacanthus pubinervius, leaves, terpenoidal glycoside, free radical, scavenging, isosbestic point, phytoconstituent, metabolites, leaves, compound.
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