Fertility-sparing surgery in the treatment of early cervical cancer is gaining acceptance in the gynecologic
oncology community as a safe alternative to radical hysterectomy. In women who desire future child-bearing, more
conservative treatments, such as radical trachelectomy with pelvic lymphadenectomy, have led to the achievement of
successful pregnancies, and viable deliveries, while maintaining equivalent oncologic outcomes. This review of a total of
984 cases of radical vaginal trachelectomy reported thus far in the literature includes patient and tumor demographics,
operative details, recurrence and fertility rates, and obstetrical outcomes. Oncologic outcomes after radical vaginal
trachelectomy appears to be equivalent to outcomes after radical hysterectomy in appropriately selected patients, making
radical vaginal trachelectomy a viable option for women desiring fertility preservation. Patients require counseling
regarding potential obstetrical complications, including preterm pre-labor rupture of membranes and preterm delivery, as
well as close oncologic follow-up. Other fertility sparing procedures such as radical abdominal trachelectomy and cone
biopsy with lymphadenectomy have also been reported in the literature, but oncologic and fertility data are not yet mature.
As more fertility-sparing procedures are performed and additional data is available on risk of recurrence, survival and
pregnancy outcomes, further analyses will be possible.
Keywords: Fertility, fertility preservation, gynecologic surgical procedures, pregnancy, radical abdominal trachelectomy,
radical vaginal trachelectomy, recurrence, survival, uterine cervical cancer, Fertility-sparing surgery
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