Abstract
Human leucocyte antigen-G (HLA-G) is a non-classical HLA class I molecule with an important role at the fetus-maternal interface, preventing fetus recognition and abortion. The role of HLA-G as an immune-modulatory and anti-inflammatory molecule has led to investigate its role in pathological conditions. In these years, HLA-G has been shown to have an important implication in inflammatory pathologies. The focus of this review is to up-date the scientific knowledge on the expression of HLA-G molecules in inflammatory conditions.
Keywords: HLA-G, immunity, immune cells, inflammation, pathology, regulation, Human leucocyte antigen-G, anti-inflammatory, HLA-G typing, Allergic disorders
Inflammation & Allergy - Drug Targets (Discontinued)
Title:New Insights into HLA-G and Inflammatory Diseases
Volume: 11 Issue: 6
Author(s): Roberta Rizzo, Daria Bortolotti, Olavio R. Baricordi and Enrico Fainardi
Affiliation:
Keywords: HLA-G, immunity, immune cells, inflammation, pathology, regulation, Human leucocyte antigen-G, anti-inflammatory, HLA-G typing, Allergic disorders
Abstract: Human leucocyte antigen-G (HLA-G) is a non-classical HLA class I molecule with an important role at the fetus-maternal interface, preventing fetus recognition and abortion. The role of HLA-G as an immune-modulatory and anti-inflammatory molecule has led to investigate its role in pathological conditions. In these years, HLA-G has been shown to have an important implication in inflammatory pathologies. The focus of this review is to up-date the scientific knowledge on the expression of HLA-G molecules in inflammatory conditions.
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Cite this article as:
Rizzo Roberta, Bortolotti Daria, R. Baricordi Olavio and Fainardi Enrico, New Insights into HLA-G and Inflammatory Diseases, Inflammation & Allergy - Drug Targets (Discontinued) 2012; 11 (6) . https://dx.doi.org/10.2174/187152812803590037
DOI https://dx.doi.org/10.2174/187152812803590037 |
Print ISSN 1871-5281 |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-4055 |
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